Plasma levels of pentosidine in diabetic patients: an advanced glycation end product.
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چکیده
منابع مشابه
Plasma levels of pentosidine in diabetic patients: an advanced glycation end product.
Nonenzymatic reactions between glucose and proteins yield advanced glycation end products (AGE) such as pentosidine. AGE accumulate in diabetic patients, alter the structure and function of tissue proteins, stimulate cellular response, and have thus been implicated in diabetic tissue damage. The present study was undertaken to assess the factors determining plasma total pentosidine level in dia...
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PURPOSE To determine whether there is an age-related increase of pentosidine in human Bruch's membranes and to localize pentosidine and carboxymethyllysine (CML), two well-characterized, advanced glycation end products (AGEs) in aged human Bruch's membranes and choroid in vivo. METHODS Human Bruch's membrane samples were isolated from the retinal pigment epithelium (RPE) and choroid and subje...
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ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 1998
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.v991681